AI revenue integrity for hematology & oncology practices

Drug units, wastage, and regimen auth errors cost hematology and oncology practices recoverable revenue every day.

Hematology and oncology bill the highest per-claim dollars in medicine, chemotherapy, biologic, and hematology drugs, complex infusion days, and tightly controlled regimens. A single J-code, wastage modifier, or missing authorization can wipe out a five-figure claim. Manual billing teams catch a fraction of the errors. Ember catches all of them.

57%denial rate reduction
100%encounters reviewed
3 daysto first results

Trusted by specialty groups and health systems

Ozark OrthopaedicsFinancial District Foot & Ankle CenterPeninsula Gastroenterology Medical GroupMVPQuantum RadiologyMoami Hand Center

Where oncology revenue leaks

The denial patterns Ember was built for

Oncology runs the highest per-claim dollars in medicine, chemotherapy and biologic drugs, complex infusion days, and tightly controlled regimens. A single J-code, wastage modifier, or missing authorization can wipe out a five-figure claim. Ember closes each gap.

01 · Drug units & wastage

High-cost J-codes denied on units and missing wastage modifiers.

Chemotherapy and biologic agents are billed by exact units against documented dose, with discarded drug reported under JW and single-dose vials attested under JZ. A unit error or a missing wastage modifier on a five-figure drug becomes a denial or a takeback. Ember keeps J-codes, units, and wastage accurate on every infusion before submission.

J9299 · J9035 · J2505 · JW · JZ

02 · Infusion administration

A full chemo day collapsing into a partial payment.

Infusion administration follows a strict hierarchy, one initial code, then sequential, concurrent, and additional-hour codes against documented start and stop times. Get the sequencing wrong and a complex multi-drug day is billed as a fraction of the work performed. Ember applies the hierarchy against the documented times so the whole day is captured.

96413 · 96415 · 96417 · 96367

03 · Regimen auth & pathways

Drugs and chair time given before coverage is confirmed.

High-cost regimens require prior authorization, step-therapy clearance, and NCCN-pathway alignment that shift constantly by payer. Treat before coverage is locked and the practice eats the drug cost. Ember confirms regimen authorization and pathway requirements and gathers documentation before the patient is in the chair.

Prior auth · NCCN pathway · step therapy

Three engines.
One source of truth.

Ember connects clinical documentation, payer policy, and contract terms into a single intelligence layer. Built for the J-codes, infusion hierarchy, and regimen authorizations oncology billing requires.

01 · Foundation

Data Engine

Bridges the clinical and the financial. Unifies documentation, drug and administration coding, payer policy, and contracts across every infusion, regimen, and provider.

D. Okafor

Chemo day #O-44910

Unified
Documentation
Infusion 0900–1215, 1 vial discarded
Coding
J92999641396415 ×2
Payer policy
BCBS · Oncology pathway
Contract
ASP + 6%

02 · Audit

Coding Engine

Reviews 100% of chemo days against national standards, payer-specific policies, your internal guidelines, and your payer contracts. Every flag carries a rule citation.

Audit#O-44910
J9299Single-dose vial, JZ missing
Flag
96417Additional hour not billed
Flag

Add JZ + 96417 — times support additional hour

CMS wastage / CPT infusion rules · confidence 0.97

03 · Recovery

Appeal Engine

Reads CARC and RARC codes, identifies the applicable medical-necessity policy and contract terms, drafts the appeal letter, packages documentation, and tracks every claim to adjudication.

Re: Claim #O-44910 · Denial CO-50

The prescribed regimen is medically necessary and on-pathway per NCCN Category 1 and meets step-therapy criteria under contract ASP + 6%

Denial received
Appeal drafted
Submitted · in review
Adjudication pending

Audit upstream.
Appeal downstream.

Two workflows do most of the work for oncology practices. The first prevents denials before they happen. The second recovers the ones that slip through.

Pre-bill audit

Catch the missing wastage modifier before the claim leaves.

Ember reviews every chemo day against coding standards, payer policy, and your contracts. Unit errors, missing JW/JZ, and under-billed infusion hours are flagged before submission, on the highest-dollar claims you bill.

  • 1

    Ingest the encounter

    Pulls infusion records, documented start/stop times, drug administration logs, and regimen authorization status from your EHR.

  • 2

    Validate against rules

    Checks J-code units, JW/JZ wastage, the infusion administration hierarchy, and regimen auth/pathway status against each payer's specific policies.

  • 3

    Recommend with citation

    Returns the suggested correction tied to the exact CMS rule, payer policy, NCCN pathway, or contract term.

  • 4

    Educate the provider

    Coding and documentation patterns drive provider-level coaching, so infusion timing and wastage capture improve across the practice.

Chemo day review#O-44910
96413Initial infusion, 1 hr
Pass
J9299Single-dose vial, JZ missing
Flag
96417Additional hour not billed
Flag

Add JZ modifier + bill 96417 — times support it

CMS wastage / CPT infusion rules · confidence 0.98

+23%

Clean-claim rate

100%

Chemo days reviewed

+5%

Net collection rate

Automated appeals

Pull. Review. Push.

When a denial occurs, Ember identifies the root cause, retrieves infusion records and regimen documentation, references payer medical-necessity policy, NCCN pathways, and contract terms, drafts the appeal, and tracks it through adjudication.

Pull13
CO-50

Regimen medical necessity

CO-151

Units exceed policy

Review8
CO-97

Admin bundled

Push10
CO-197

Step therapy not met

Learn
PAID

NCCN pathway appeal

-57%

Denial rate

-45%

Cost to collect

+9.3%

Net revenue per infusion

The full revenue cycle

From eligibility to adjudication. Covered.

Audit and appeals are the workhorses, but Ember protects oncology revenue at every stage of the cycle.

Eligibility Verification

Confirms active coverage and drug-benefit structure before treatment, and flags coverage gaps on high-cost regimens before they become takebacks.

Prior Auth & Step Therapy

Confirms regimen authorization, step-therapy and pathway requirements, gathers the documentation payers require, and submits before the patient is in the chair.

AI Medical Coding

Reviews 100% of chemo days, J-code units, JW/JZ wastage, and the infusion administration hierarchy, against national standards and payer rules before claims submit.

Pre-bill Audit

Predicts and prevents denials before claims go out, catching unit errors, missing wastage modifiers, and under-billed infusion hours before they generate write-offs.

Denial Management

Full appeal lifecycle for every oncology denial type, medical necessity, units, bundling, step therapy, and auth failure, tracked to adjudication.

Underpayment Recovery

Parses contracts to model what each drug and infusion should pay under ASP-based terms, then surfaces line-item underpayments at scale.

High-dollar oncology revenue, recovered

-57%

denial rate

-45%

cost to collect

100%

chemo days audited

3 days

to first results

Based on Ember AI benchmarks across customer practices. Results vary by payer mix and specialty.

Frequently asked questions

Everything you need to know about how Ember fits into your revenue cycle.

Yes. Ember AI connects seamlessly with all major EHRs and PMS platforms, including Epic, Oracle Cerner, athenahealth, and eClinicalWorks, as well as payer portals. Our standards-based integrations automate prior authorization, eligibility verification, and claims submission, allowing you to preserve existing infrastructure while modernizing the revenue cycle.
Ember AI deployments are measured in weeks, not months. Most organizations complete pilot launch in under 30 days and scale enterprise-wide within a quarter. We provide a structured onboarding playbook, technical support, and change-management guidance so your teams achieve measurable ROI rapidly with minimal IT lift.
Yes. Ember AI is fully HIPAA and SOC 2 Type II compliant and signs Business Associate Agreements (BAAs) with all covered entities. Protected Health Information (PHI) is encrypted in transit and at rest, supported by role-based access controls, detailed audit logging, and continuous monitoring. Your organization retains complete ownership and control of its data.
Health systems, MSOs, and health plans using Ember AI typically achieve:

- 50-75% reduction in FTE hours
- Faster cash acceleration
- Prevent 55%+ of denials

We provide ROI benchmarks and dashboards so you can track outcomes from day one.
Yes. Ember's coding and scrubbing logic is specialty-aware, it understands chemotherapy, biologic, and hematology drug J-codes, the infusion administration hierarchy, regimen authorization, and NCCN-aligned documentation, and validates claims against payer medical-necessity criteria before submission.
Ember keeps J-codes, units, and documented wastage (JW/JZ modifiers) accurate on every chemotherapy and biologic agent, so the highest-dollar claims in your practice are paid in full instead of denied or taken back on a single infusion.
Yes. Ember applies the initial, sequential, concurrent, and additional-hour infusion hierarchy against documented start and stop times, so a full chemotherapy day is billed completely instead of collapsing into a partial payment.
Yes. Ember checks eligibility, confirms regimen authorization and step-therapy/pathway requirements, gathers documentation from your EHR, and submits through payer portals, so drugs and chair time aren't given without coverage in place.
Ember connects to your existing EHR/PMS and payer systems with standards-based integrations, no rip-and-replace. Most teams pilot in days and see measurable ROI before scaling across service lines.

See what your oncology practice is leaving on the table

Bring us 30 days of denial data. We'll show you where the revenue is and exactly how Ember would recover it.