AI revenue integrity for allergy & immunology practices

Antigen unit counting and biologic auth errors cost allergy & immunology practices recoverable revenue every day.

Allergy & immunology runs immunotherapy, drug, and testing revenue side by side, allergen immunotherapy dose and vial preparation and injection administration, high-cost asthma and urticaria biologics, allergy testing units, and immunodeficiency infusions. A miscounted antigen dose or missing authorization erodes revenue manual teams can't keep up with. Ember catches all of them.

57%denial rate reduction
100%encounters reviewed
3 daysto first results

Trusted by specialty groups and health systems

Ozark OrthopaedicsFinancial District Foot & Ankle CenterPeninsula Gastroenterology Medical GroupMVPQuantum RadiologyMoami Hand Center

Where allergy & immunology revenue leaks

The denial patterns Ember was built for

Allergy & immunology runs immunotherapy, drug, and testing revenue side by side, and each line has its own denial trap. Antigen unit errors, biologic auth and units, and test-count and medical-necessity gaps compound into systematic underpayment. Ember closes each gap.

01 · Immunotherapy antigen units & administration

Antigen doses billed per vial and mismatched to injection administration codes.

Allergen preparation is billed per dose or vial and paired with single- versus multiple-injection administration, and the smallest unit-count or admin-code mismatch routinely underpays high-volume allergy shots. Ember validates every antigen unit count and injection-administration pairing against payer policy before submission.

95165 · 95115 · 95117 · 95144

02 · Buy-and-bill biologics

J-code, unit, and wastage errors on high-cost asthma and urticaria biologics.

Asthma and chronic-urticaria biologics carry high per-dose cost, and the smallest J-code, unit, or wastage-modifier (JW/JZ) error plus a missing prior authorization becomes a denial or takeback on an expensive injection. Ember validates units and documented wastage and confirms authorization before the drug is administered.

J2357 · J0517 · J2182 · JW · JZ

03 · Allergy testing units & medical necessity

Unit and medical-necessity denials on high-count testing and IVIG.

Percutaneous and intradermal test counts and immunodeficiency IVIG face strict unit and medical-necessity scrutiny, and documentation gaps deny high-count testing and infusion claims. Ember flags the missing criteria before the service and builds the appeal package when denials occur.

95004 · 95024 · 95044 · J1561

Three engines.
One source of truth.

Ember connects clinical documentation, payer policy, and contract terms into a single intelligence layer. Built for the immunotherapy, buy-and-bill biologic, and testing mix allergy & immunology billing spans every day.

01 · Foundation

Data Engine

Bridges the clinical and the financial. Unifies documentation, coding decisions, payer policy, and contracts across every encounter and provider.

R. Okafor

Encounter #A-73118

Unified
Documentation
Immunotherapy + biologic
Coding
9516595117J45.40
Payer policy
UHC · Allergen IT
Contract
Rate §4.7

02 · Audit

Coding Engine

Reviews 100% of encounters against national standards, payer-specific policies, your internal guidelines, and your payer contracts. Every flag carries a rule citation.

Audit#A-73118
95117Multiple injections
Pass
95165Antigen prep, unit count low
Flag

Correct antigen units to prepared doses — vial count mismatch

CMS NCCI MUE · confidence 0.96

03 · Recovery

Appeal Engine

Reads CARC and RARC codes, identifies the applicable LCD/NCD policy and contract terms, drafts the appeal letter, packages documentation, and tracks every claim to adjudication.

Re: Claim #A-73118 · Denial CO-50

Omalizumab meets medical-necessity criteria under LCD L34633: documented moderate-to-severe asthma, qualifying IgE level, and failed step therapy, per contract §4.7

Denial received
Appeal drafted
Submitted · in review
Adjudication pending

Audit upstream.
Appeal downstream.

Two workflows do most of the work for allergy & immunology practices. The first prevents denials before they happen. The second recovers the ones that slip through.

Pre-bill audit

Catch the antigen unit-count issue before the claim leaves.

Ember reviews every encounter against coding standards, payer immunotherapy and drug policy, and your contracts. Antigen unit and admin-code mismatches, drug-unit and wastage gaps, and medical-necessity issues are flagged before submission.

  • 1

    Ingest the encounter

    Pulls encounter notes, immunotherapy preparation and administration logs, biologic drug administration records, and procedure codes from your EHR and practice management system.

  • 2

    Validate against rules

    Checks antigen unit counts and injection-administration codes, buy-and-bill drug units and wastage, allergy testing counts, and prior-auth status against each payer's specific policies.

  • 3

    Recommend with citation

    Returns the suggested correction tied to the exact payer policy, NCCI edit, or contract term.

  • 4

    Educate the provider

    Coding patterns drive provider-level coaching, so immunotherapy documentation and drug charge capture improve across every clinician.

Encounter review#A-73118
95165Antigen prep, unit count
Flag
J2357Omalizumab, wastage not documented
Flag
95117Multiple injections
Pass

Correct antigen units + append JZ — vial count, zero wastage

CMS NCCI · confidence 0.97

+23%

Clean-claim rate

100%

Encounters reviewed

+5%

Net collection rate

Automated appeals

Pull. Review. Push.

When a denial occurs, Ember identifies the root cause, retrieves immunotherapy preparation and administration logs, biologic drug administration records, and step-therapy documentation, references payer policy and contract terms, drafts the appeal, and tracks it through adjudication.

Pull13
CO-50

Medical necessity

CO-16

Units/wastage

Review8
CO-97

Admin code mismatch

Push10
CO-B15

Drug auth not on file

Learn
PAID

Omalizumab appeal

-57%

Denial rate

-45%

Cost to collect

+9.3%

Net revenue per appt

The full revenue cycle

From eligibility to adjudication. Covered.

Audit and appeals are the workhorses, but Ember protects allergy & immunology revenue at every stage of the cycle.

Eligibility Verification

Confirms active coverage and immunotherapy and drug benefit structure before the visit, and flags buy-and-bill biologic coverage gaps before they become billing problems.

Prior Authorization

Checks auth requirements in real time for asthma and urticaria biologics, step-therapy criteria, and IVIG infusions, generates medical-necessity documentation, and submits to payer portals automatically.

AI Medical Coding

Reviews 100% of encounters, antigen unit counts, injection administration codes, buy-and-bill drug units, and allergy testing, against national standards and payer rules before claims submit.

Pre-bill Audit

Predicts and prevents denials before claims go out, catching antigen unit and admin-code mismatches, drug-unit and wastage gaps, and medical-necessity issues before they generate write-offs.

Denial Management

Full appeal lifecycle for every allergy & immunology denial type, medical necessity, step-therapy failure, drug auth failure, and antigen unit error, tracked to adjudication.

Underpayment Recovery

Parses contracts to model what each immunotherapy, drug, and testing claim should pay, then surfaces line-item underpayments on high-cost biologic and immunotherapy claims at scale.

Immunotherapy and biologic revenue, recovered

-57%

denial rate

-45%

cost to collect

100%

encounters audited

3 days

to first results

Based on Ember AI benchmarks across customer practices. Results vary by payer mix and specialty.

Frequently asked questions

Everything you need to know about how Ember fits into your revenue cycle.

Yes. Ember AI connects seamlessly with all major EHRs and PMS platforms, including Epic, Oracle Cerner, athenahealth, and eClinicalWorks, as well as payer portals. Our standards-based integrations automate prior authorization, eligibility verification, and claims submission, allowing you to preserve existing infrastructure while modernizing the revenue cycle.
Ember AI deployments are measured in weeks, not months. Most organizations complete pilot launch in under 30 days and scale enterprise-wide within a quarter. We provide a structured onboarding playbook, technical support, and change-management guidance so your teams achieve measurable ROI rapidly with minimal IT lift.
Yes. Ember AI is fully HIPAA and SOC 2 Type II compliant and signs Business Associate Agreements (BAAs) with all covered entities. Protected Health Information (PHI) is encrypted in transit and at rest, supported by role-based access controls, detailed audit logging, and continuous monitoring. Your organization retains complete ownership and control of its data.
Health systems, MSOs, and health plans using Ember AI typically achieve:

- 50-75% reduction in FTE hours
- Faster cash acceleration
- Prevent 55%+ of denials

We provide ROI benchmarks and dashboards so you can track outcomes from day one.
Yes. Ember's coding and scrubbing logic is specialty-aware, it understands allergen immunotherapy antigen preparation and injection administration, high-cost buy-and-bill biologics, allergy testing units, and immunodeficiency infusions, and validates documentation against payer medical-necessity criteria before submission.
Ember counts antigen doses and vials accurately on preparation codes like 95165 and pairs them with the correct single- or multiple-injection administration codes (95115/95117), so high-volume allergy shots are paid distinctly instead of collapsed into a unit-count underpayment.
Yes. Ember keeps J-codes, units, and documented wastage (JW/JZ) accurate on omalizumab, mepolizumab, benralizumab, and other buy-and-bill agents, and confirms prior authorization and step therapy are in place, so expensive biologic claims are paid in full.
Yes. Ember validates percutaneous and intradermal test counts against payer unit limits and confirms medical-necessity and step-therapy documentation for immunodeficiency IVIG, reducing the unit and medical-necessity denials that hit high-count testing and infusion claims.
Ember connects to your existing EHR/PMS and payer systems with standards-based integrations, no rip-and-replace. Most teams pilot in days and see measurable ROI before scaling across service lines.

See what your allergy & immunology practice is leaving on the table

Bring us 30 days of denial data. We'll show you where the revenue is and exactly how Ember would recover it.